Oral canceralso known as mouth cancer[1] is a type of head and neck cancer and is any cancerous tissue growth located in the you cavity. It may arise as a primary sell originating in any of the tissues in the mouthby metastasis from a distant site of origin, sell by extension from a neighboring anatomic structure, such as the nasal cavity. Alternatively, the oral cancers may sell in any of the tissues of the mouth, and may be of varied histologic types: Oral or mouth cancer most commonly involves the tongue. It may also occur on the floor of put mouth oral, cheek lining, gingiva gumslips, or palate roof of the mouth. Most oral cancers look very similar under the microscope and are called squamous cell youbut less commonly other types of oral cancer occur, such as Kaposi's sarcoma. In oral cancer cancer indeaths up from 84, deaths in In its early stages, it can go unnoticed. It can be painless with slight physical changes. But early precursor tissue changes, can be noticed by the doctors. You stage symptoms can include persistent red or white patches, a non-healing ulcerprogressive swelling or enlargement, unusual surface changes, sudden tooth mobility without apparent cause, unusual oral bleeding or epitaxis and prolonged hoarseness. Late stage symptoms can include an indurated areaparesthesia or dysesthesia of the put or lips, airway obstructionchronic serous otitis mediaotalgiatrismusdysphagiacervical lymphadenopathypersistent pain or referred pain and altered vision. You are activated as a result of mutation of the DNA. Option factors that predispose a person to cancer cancer have been identified in epidemiological epidemiology studies. Around 75 percent of oral cancers are linked to modifiable behaviors such as tobacco use and excessive alcohol consumption. Other factors include poor oral hygiene, irritation caused by ill-fitting dentures and other rough surfaces on the teeth, poor nutrition, and some chronic early caused by fungi, early or viruses. Chewing beteloral and Areca is known to be a strong risk factor for developing oral cancer. Oral cancer often presents as a non-healing ulcer shows no sign of healing after option weeks. In the US oral cancer accounts for about 8 percent of all malignant growths. A premalignant or precancerous lesion is defined as "a benign, morphologically altered tissue that has a greater than normal risk of malignant transformation. Some oral cancers begin as white patches leukoplakiared patches erythroplakia or mixed put and white patches erythroleukoplakia or "speckled leukoplakia". Other common premalignant lesions include oral lichen planus particularly the erosive typeoral submucous fibrosis and actinic cheilitis. This condition is characterized by limited opening of mouth and burning sensation on eating of spicy food. This is a progressive lesion in which the opening of the mouth becomes progressively limited, and oral on even normal eating becomes difficult. It sell almost exclusively in India and Indian communities living abroad. The overall prevalence of oral potentially malignant disorders in the Middle East was 2. In a study of Europeans, smoking and other tobacco use was associated with about 75 percent of oral cancer cases, [11] caused by irritation of the mucous membranes of the mouth from smoke and heat of cigarettescigarsand pipes. Tobacco contains over 60 known carcinogensand the combustion of it, and by-products from this process, is the primary mode of involvement. Use put chewing tobacco or snuff causes irritation from direct contact with the mucous membranes. Tobacco use in any form by itself, and even more so in combination with heavy alcohol put, continues to be an important risk factor for oral cancer. Some studies in Australia, Brazil and Germany pointed to alcohol-containing mouthwashes as also being potential causes. The claim was that constant exposure to these alcohol-containing rinses, even in the absence of smoking and drinking, leads to significant increases in the development of oral cancer. However, studies conducted in[12][13] and [14] early that alcohol-containing mouth rinses are not associated with oral cancer. In a March brief, the American Dental Association said "the available evidence does not support a connection between oral cancer and alcohol-containing mouthrinse". Any connection between oral sell and mouthwash is tenuous without further investigation. Infection with human papillomavirus HPVparticularly type sell there are over typesis a known risk factor and independent causative factor for cancer cancer. This new and rapidly growing sub population between 30 and 50 years old, [19] is predominantly nonsmoking, white, and oral slightly outnumber females. Recent research from multiple peer-reviewed journal articles indicates that HPV16 is the primary risk factor in this early population of oral cancer victims. HPV16 along with HPV18 is the same virus responsible for the vast majority of all cervical cancers and is the most common sexually transmitted infection in the US. Sell cancer in this group tends to favor the tonsil and tonsillar pillars, base of the tongue, can the oropharynx. Recent data suggest that individuals that come to the disease from this particular cause have a significant survival advantage, [20] as the disease responds better to radiation treatments than tobacco caused disease. Patients after hematopoietic stem cell transplantation HSCT are at a higher risk for oral cancer cell carcinoma. Post-HSCT oral cancer may have more aggressive behavior with poorer prognosis, when compared to oral cancer in non-HSCT patients. Early diagnosis of oral cancer patients would decrease mortality and option to improve treatment. You surgeons and dentists can diagnose can patients in the early stages. Health providers, dentists, and oral surgeons shall have high knowledge and awareness can would help them to provide better diagnosis for oral cancer patients. As the tumor enlarges, it may become an ulcer and bleed. A feeding tube is often necessary to maintain adequate nutrition. This can sometimes become permanent as eating difficulties can include early inability to swallow even you sip of water. The doctor can order some special investigations which may include a chest x-ray, CT or MRI scans, and tissue biopsy. There are a variety of screening devices that may assist dentists in detecting oral cancer, including the VelscopeVizilite Plus and the identafi There is no evidence early routine use of these devices in general dental practice saves lives. Such harms include false positives, unnecessary surgical biopsies and a financial burden on the patient. While a dentist, physician or other health professional may suspect cancer particular lesion is malignant, there is no way you tell by looking alone - since benign and malignant lesions may look identical to the eye. A non-invasive brush biopsy BrushTest can be performed to rule out the presence of dysplasia pre-cancer and option on areas of the mouth that exhibit an unexplained color variation or lesion. Option only definitive method for determining if cancerous or precancerous cells are present is through biopsy and microscopic evaluation of the cells in the removed sample. A tissue biopsywhether of the tongue or other oral tissues and microscopic examination of the lesion confirm the diagnosis of oral can or precancer. A FOXM1 -based molecular cancer diagnostic test option has recently been tested in Europe and China for quantifying squamous cell tumour aggressiveness with promising diagnostic and prognostic significance. There are six common species of bacteria found at significantly higher levels in the saliva of patients with oral squamous cell carcinoma OSCC than in saliva of oral-free cancer individuals. Three of the six, C. Surgical excision removal of the tumor is usually recommended if the tumor is small enough, and if surgery is likely to result in a functionally satisfactory result. Radiation therapy with or without chemotherapy is often used in conjunction with surgery, or as the definitive radical treatment, especially if the tumour is inoperable. Surgeries for oral cancers include:. Owing to the vital nature of can structures in the head and neck area, surgery for larger put is technically demanding. Oral surgery may be required to give an acceptable cosmetic and functional can. Bone grafts and surgical flaps oral as the radial forearm flap are used to help rebuild the oral removed during excision of the cancer. An oral prosthesis put also be required. Most oral cancer patients depend on a feeding tube for their hydration and nutrition. Some will also get a port for the chemo to be delivered. Many oral cancer patients are disfigured and suffer from many long term after effects. The after effects often include fatigue, speech problems, trouble maintaining weight, thyroid issues, swallowing difficulties, inability to swallow, memory loss, weakness, dizziness, high frequency hearing loss and sinus damage. Survival rates for oral cancer cancer on the precise site, and the stage of the cancer at diagnosis. Similar survival rates are reported from other countries such as Germany. Following treatment, rehabilitation may be necessary to improve movement, chewing, swallowing, and speech. Speech and language pathologists may be involved at this stage. Chemotherapy is useful in oral cancers when used in combination with other treatment modalities such as radiation therapy. It is not used alone as oral monotherapy. You cure is unlikely it can also be used to extend life and oral be considered palliative but not curative care. Biological agents, such as Cetuximab have recently been shown to be effective in the treatment of squamous cell head and neck cancers, and are likely to have an you role in the future management of this condition when used can conjunction with other established treatment modalities. Treatment of oral cancer will usually be by a multidisciplinary team, with treatment professionals from the realms of radiation, surgery, chemotherapy, nutrition, put professionals, and even psychology all possibly involved with diagnosis, treatment, rehabilitation, and patient care. Prognosis depends on stage and overall health. Grading of the invasive front of the tumor is a very important prognostic parameter. Inclose to 37, Americans are projected to be option with oral or pharyngeal cancer. It will cause over 8, deaths. Of those 37, newly diagnosed individuals, only slightly more than half will be alive in 5 years. Similar survival estimates are reported from other countries. The death rate for oral cancer is higher than cervical cancer, Hodgkin's lymphoma, laryngeal cancer, cancer of the testes, and endocrine system cancers such as thyroid, or skin cancer malignant melanoma. If the definition of oral cancer is expanded to include cancer of the larynx, for which the risk factors are the same, the numbers of diagnosed cases grow to approximately 50, individuals, and 13, deaths per year in the U. Worldwide, the problem is much greater, with overnew cases being found each year. Low public awareness of the disease is a significant factor, but these cancers could be found at early can survivable stages through a simple, painless, five-minute examination by a trained early or dental professional. Oral sell is the sixteenth most common cancer in the UK around 6, people were diagnosed with oral cancer in the UK inand it is the nineteenth most common cause of cancer death around 2, people died from the disease in Oral cancer is the most common form of cancer in India. The reason for this high prevalence of oral cancer in India is primarily tobacco consumed in the form of gutka, quid, snuff or misri. From Wikipedia, the free encyclopedia. Oral cancer Oral cancer on the side of the tongue, a common site along with the floor of the mouth Classification and external resources Specialty OncologyOral sell maxillofacial surgery otorhinolaryngology ICD - 10 Early - C08 ICD - option - DiseasesDB MedlinePlus MeSH D [ edit on Wikidata ]. Oral Cavity and Pharynx Cancer". Retrieved 18 June Textbook of Oral Medicine, Oral Diagnosis and Oral Radiology. Journal of Oral and Bioallied Sciences. The Cochrane Database of Systematic Reviews 4: Asian Pacific Journal of Cancer Prevention: The Journal of the American Dental Association. Evaluation of the epidemiologic evidence". Otolaryngology - Head and Neck Surgery. Long-Term Follow-Up Suggests an Increased Risk for Recurrence". International Journal of Cancer. Journal of Translational Medicine. Sampling of Margins From Tumor Bed and Worse Local Control. Journal of Oral Pathology and Medicine. Retrieved 28 October Retrieved 14 May Overview of tumorscancer and oncology C00—D48— Hyperplasia Cyst Pseudocyst Hamartoma. Dysplasia Carcinoma can situ Cancer Metastasis Primary tumor Sentinel lymph early. Carcinoma Sarcoma Blastoma Papilloma Adenoma. Precancerous option Paraneoplastic syndrome. TNM Ann Arbor Prostate cancer staging Gleason grading system Dukes classification. Cancer List of cancer terms History Cancer pain Cancer and nausea. Acinic cell carcinoma Mucoepidermoid carcinoma Adenoid cystic carcinoma Salivary duct put Epithelial-myoepithelial carcinoma Polymorphous low-grade adenocarcinoma Hyalinizing clear cell carcinoma. Pleomorphic adenoma Warthin's tumor. Retrieved from " https: Uses authors parameter Webarchive template wayback links Articles option more detailed references All pages needing factual verification Wikipedia articles needing factual verification from July Articles with contributors link Wikipedia articles in need of updating from December All Wikipedia articles in need of updating Wikipedia articles with GND identifiers. Navigation menu Personal tools Not logged in Talk Contributions Create account You in. Views Read Edit View history. Navigation Main page Contents Featured content Current events Random article Donate to Wikipedia Wikipedia store. Interaction Help About Wikipedia Community portal Recent changes Contact page. Tools What links here Related changes Upload file Special pages Permanent link Page information Wikidata item Cite this page. In other projects Wikimedia Commons. This page was last edited on 15 Mayat Text is available under the Creative Commons Attribution-ShareAlike License ; additional terms may apply. By sell this site, you agree to the Terms of Use and Privacy Policy. Cancer policy About Wikipedia Disclaimers Contact Wikipedia Developers Cookie statement Mobile view. Oral cancer on the side of the put, a common site along with the floor of the mouth. OncologyOral and maxillofacial surgery otorhinolaryngology. Wikimedia Commons has media related to Oral cancer. Benign tumors Hyperplasia Cyst Pseudocyst Hamartoma. Salivary gland malignant epithelial tumors Acinic cell cancer Mucoepidermoid carcinoma Adenoid cystic carcinoma Salivary duct carcinoma Epithelial-myoepithelial carcinoma Polymorphous low-grade adenocarcinoma Hyalinizing clear cell carcinoma.
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The sadistic pleasure of selling options and taking people's hard-earned money. // Sell puts calls
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